Travelling-wave ion mobility and negative ion fragmentation of high-mannoseN-glycans
نویسندگان
چکیده
منابع مشابه
Collision cross section calibrants for negative ion mode traveling wave ion mobility-mass spectrometry.
Unlike traditional drift-tube ion mobility-mass spectrometry, traveling-wave ion mobility-mass spectrometry typically requires calibration in order to generate collision cross section (CCS) values. Although this has received a significant amount of attention for positive-ion mode analysis, little attention has been paid for CCS calibration in negative ion mode. Here, we provide drift-tube CCS v...
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Glycosylation is one of the most common post-translational modifications occurring in proteins. A detailed structural characterization of the involved carbohydrates, however, is still one of the greatest challenges in modern glycoproteomics, since multiple regio- and stereoisomers with an identical monosaccharide composition may exist. Recently, ion mobility-mass spectrometry (IM-MS), a techniq...
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Since the introduction of travelling wave (T-Wave)-based ion mobility in 2007 a large number of research laboratories have embraced the technique, particularly those working in the field of structural biology. The development of software to process the data generated from this technique, however, has been limited. We present a novel software package that enables the processing of T-Wave ion mob...
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Gas phase ion mobility measurements can resolve structural isomers for polyatomic ions and provide information about their geometries. A new experimental apparatus for performing high-resolution ion mobility measurements is described. The apparatus consists of a pulsed laser vaporization/desorption source coupled through an ion gate to a 63-cm-long drift tube. The ion gate is a critical compone...
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ژورنال
عنوان ژورنال: Journal of Mass Spectrometry
سال: 2016
ISSN: 1076-5174
DOI: 10.1002/jms.3738